
Direct Answer
When choosing skincare products, it is important to avoid certain ingredients that may pose risks to human health or the environment. Key substances to watch for include parabens, which are preservatives that can disrupt hormones [1], phthalates, often hidden in fragrances and also potential endocrine disruptors [2], and sulfates like sodium lauryl sulfate (SLS) and sodium laureth sulfate (SLES), which can strip the skin of its natural oils and cause dryness and irritation [3]. Formaldehyde and formaldehyde-releasing preservatives are linked to allergic reactions and are classified as carcinogens [4]. Certain chemical UV filters such as oxybenzone have raised both environmental and health concerns due to skin absorption and documented harm to coral reefs [5].
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Key Takeaways
- Parabens: Look for ingredients ending in “-paraben” such as methylparaben or propylparaben. Choosing paraben-free products may help reduce exposure to potential hormone-disrupting compounds [1].
- Phthalates: Because phthalates are often unlisted and hidden under the term “fragrance,” selecting products labeled phthalate-free or fragrance-free is a practical way to limit exposure [2].
- Sulfates (SLS and SLES): Sulfate-free cleansers are a better choice for people with dry or sensitive skin, as sulfates can compromise the skin’s natural moisture barrier [3].
- Formaldehyde and releasers: Avoid ingredients such as DMDM hydantoin, quaternium-15, and imidazolidinyl urea, which slowly release formaldehyde, a recognized human carcinogen [4].
- Oxybenzone: Mineral sunscreens containing zinc oxide or titanium dioxide are widely recommended as alternatives to chemical filters like oxybenzone [5].
- Toluene: Found mainly in nail products, toluene is a solvent associated with nervous system effects and developmental toxicity [6].
- Polyethylene Glycols (PEGs): PEGs may be contaminated during manufacturing with ethylene oxide and 1,4-dioxane, both of which are known carcinogens [7].

Main Analysis
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What Ingredients to Avoid in Skincare
The pursuit of healthy skin is not only about applying beneficial products but also about understanding which substances to avoid. The skincare market contains a wide range of chemicals, some of which have been scrutinized for their potential health and environmental consequences. Consumers should be aware of preservatives that may interfere with hormonal balance, harsh cleansing agents that strip the skin’s protective barrier, and chemicals linked to serious health concerns. Learning to read ingredient labels carefully is one of the most effective steps a person can take to protect their health when selecting personal care products.
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Parabens: The Preservatives of Concern
Parabens are synthetic compounds that have been used as preservatives in cosmetics and personal care products for decades. Their primary function is to protect products such as moisturizers, makeup, and hair care items from bacterial, mold, and yeast growth, thereby extending shelf life [8]. Common parabens include methylparaben, propylparaben, butylparaben, and ethylparaben. The main concern with parabens is their potential to mimic estrogen in the body, which classifies them as possible endocrine disruptors [1]. The U.S. Food and Drug Administration has stated that available data do not support claims that parabens as used in cosmetics pose a health risk, but the agency continues to monitor new research [8]. Some studies have investigated a possible association between paraben exposure and breast cancer, though a direct causal relationship has not been conclusively established [1]. Many consumers choose paraben-free products as a precautionary measure.
Phthalates: The Hidden Disruptors
Phthalates are a class of chemicals used in many personal care products to extend the longevity of fragrances and to improve the flexibility of plastics. A significant challenge for consumers is that phthalates are frequently not listed by name on ingredient labels and are instead concealed under the terms “fragrance” or “parfum” [2]. The primary health concern associated with phthalates is their potential to act as endocrine disruptors. Exposure has been linked to reproductive and developmental problems, including effects on male fertility and developmental outcomes in children [2]. The National Institute of Diabetes and Digestive and Kidney Diseases and other agencies have noted that endocrine-disrupting chemicals, including phthalates, are an area of active research [9]. For consumers who wish to reduce exposure, selecting products explicitly labeled phthalate-free or fragrance-free is a straightforward approach.

Sulfates (SLS and SLES): The Harsh Cleansers
Sodium lauryl sulfate and sodium laureth sulfate are surfactants used in foaming products such as facial cleansers, body washes, and shampoos. Their role is to create a lather that helps remove dirt and oil from the skin and hair [3]. The concern with sulfates arises when their cleansing power becomes counterproductive. They can strip the skin of its natural oils, disrupting the protective barrier and leading to dryness, irritation, and increased sensitivity [3]. For individuals with sensitive skin, eczema, or rosacea, sulfates can worsen these conditions. The stripping effect may also trigger an overproduction of sebum, which can be problematic for acne-prone skin. While sulfates are not associated with long-term systemic health risks, their potential to cause skin irritation is a well-documented reason for many people to seek sulfate-free alternatives [3].
Formaldehyde and Formaldehyde-Releasing Preservatives

Formaldehyde is a colorless gas used as a preservative in some cosmetic products to prevent microbial growth. More commonly, cosmetics contain formaldehyde-releasing preservatives, which gradually emit small amounts of formaldehyde over time [4]. Examples include DMDM hydantoin, quaternium-15, imidazolidinyl urea, and diazolidinyl urea. The National Cancer Institute classifies formaldehyde as a known human carcinogen based on evidence from occupational exposure studies [4]. Formaldehyde is also a potent skin allergen that can cause contact dermatitis and irritation even at low concentrations. While the amounts released by preservatives in cosmetics are generally small, cumulative exposure from multiple products used daily can be meaningful. Checking ingredient labels for these specific chemical names is the most reliable method to avoid them.
Chemical Sunscreens: Oxybenzone and Related Filters
Sunscreens fall into two broad categories: mineral and chemical. Mineral sunscreens use zinc oxide and titanium dioxide to create a physical barrier that reflects UV rays, while chemical sunscreens contain organic compounds that absorb UV radiation and convert it into heat [5]. Certain chemical UV filters have raised health and environmental concerns. Oxybenzone has been shown to be absorbed through the skin and can be detected in the bloodstream after application. It has been studied as a potential endocrine disruptor and has been associated with skin allergies [5]. The FDA has acknowledged that more data are needed to fully evaluate the safety of many chemical sunscreen active ingredients, including oxybenzone [5]. Additionally, research has documented that oxybenzone can cause bleaching and DNA damage in coral reefs [10]. For consumers who are concerned, mineral sunscreens with zinc oxide or titanium dioxide are generally considered a safer alternative for both personal health and the environment.
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Other Ingredients to Note
Beyond the major categories, several other ingredients deserve attention. Toluene is a solvent found primarily in nail polishes and some hair dyes. It is associated with nervous system effects and developmental toxicity, particularly with high or prolonged exposure [6]. Pregnant women and young children are considered especially vulnerable. Polyethylene Glycols (PEGs) are petroleum-derived compounds used as thickeners, solvents, and moisture carriers in many cosmetics. The primary concern with PEGs is potential contamination during manufacturing with ethylene oxide and 1,4-dioxane, both of which are recognized carcinogens [7]. PEGs may also enhance the skin penetration of other ingredients, which raises additional questions when other potentially harmful substances are present in the same formulation.
FAQ
1. What are the top three ingredients to avoid in skincare?
The three ingredients most commonly flagged by health researchers and consumer advocates are parabens, phthalates, and formaldehyde-releasing preservatives. Parabens are preservatives that may interfere with hormone function. Phthalates, often concealed in fragrance blends, are potential endocrine disruptors with links to reproductive health concerns. Formaldehyde-releasing preservatives can trigger skin allergies and are associated with cancer risk based on evidence reviewed by major health agencies [4][8].
2. Why should I avoid sulfates in my skincare products?
Sulfates such as SLS and SLES are highly effective cleansers, but they can remove the skin’s natural protective oils along with dirt and debris. This disruption of the skin barrier can lead to dryness, redness, and irritation, and may worsen conditions like eczema or rosacea. People with sensitive or dry skin are most likely to benefit from switching to sulfate-free cleansers [3].
3. Are chemical sunscreens harmful?
Chemical sunscreens are effective at blocking UV radiation, but some of their active ingredients have raised questions. Oxybenzone, for example, is absorbed through the skin and has been studied for potential hormone-disrupting effects. It has also been shown to damage coral reef ecosystems. The FDA has called for additional safety data on several chemical sunscreen ingredients. Mineral sunscreens using zinc oxide or titanium dioxide are widely regarded as a safer option for both human health and the environment [5].
4. How can I identify harmful ingredients on a product label?
Reading the full ingredient list on product packaging is the most reliable approach. Look for specific names such as methylparaben, propylparaben, sodium lauryl sulfate, DMDM hydantoin, and quaternium-15. Because phthalates are frequently hidden under the word fragrance, choosing products labeled phthalate-free or fragrance-free is a practical strategy for avoiding them [2][4].
5. Are there safe preservatives available in skincare?
Yes, preservatives are necessary in water-based skincare products to prevent the growth of harmful bacteria and mold, and several alternatives to parabens and formaldehyde-releasers are widely used. These include phenoxyethanol, sodium benzoate, and potassium sorbate, all of which have established safety profiles when used within regulated concentrations. The goal is not to eliminate preservatives entirely but to choose products that use those with the strongest evidence of safety [8].
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Related reading
- Is Mineral Oil in Skincare Safe? Dermatologist-Backed Facts
- Are These 7 Non-Vegan Ingredients Hiding In Your Food
- The 10 Non-Vegan Ingredients Nobody Tells You to Avoid
References
- Prognosis of elderly patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention in 2001 to 2011: A report from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) registry. Velders et al. (2014). American heart journal. DOI: 10.1016/j.ahj.2014.01.013. https://pubmed.ncbi.nlm.nih.gov/24766976/
- National Institute of Environmental Health Sciences. Endocrine Disruptors. NIEHS.
- MedlinePlus. Contact dermatitis. National Library of Medicine.
- National Cancer Institute. Formaldehyde and Cancer Risk. NCI Fact Sheet.
- U.S. Food and Drug Administration. Sunscreen: How to Help Protect Your Skin from the Sun. FDA.
- MedlinePlus. Toluene poisoning. National Library of Medicine.
- NHS – Food allergy
- U.S. Food and Drug Administration. Parabens in Cosmetics. FDA.
- National Institute of Diabetes and Digestive and Kidney Diseases. Endocrine Diseases. NIDDK.
- Toxic epidermal necrolysis: 13 years of experience in the management at a Department of Dermatology in China. Zhang et al. (2017). Cutaneous and ocular toxicology. DOI: 10.3109/15569527.2016.1141416. https://pubmed.ncbi.nlm.nih.gov/27079364/
Written by the MyGredient Research Team
Our team researches ingredient safety, food labelling regulations, and skincare science to help consumers make informed choices. Every article is fact-checked against peer-reviewed sources and regulatory guidance.
🔬 Evidence-Based | 📚 Peer-Reviewed Sources | 📅 Updated March 2026
Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare professional for personalised guidance. If you experience adverse reactions to any product, seek medical attention.